How Assess Drugs in the Treatment of Acute Bipolar Mania?
نویسندگان
چکیده
منابع مشابه
How to Assess Drugs in the Treatment of Acute Bipolar Mania?
Bipolar affective disorder is a serious mental disease associated with significant morbidity and mortality. Good-quality research available to guide treatment strategies remains insufficient, particularly with regard to manic or hypomanic episodes. A critical review of the various stages of mania might be helpful for pharmaceutical companies and investigators as a prerequisite for the clinical ...
متن کاملPharmacologic agents for the treatment of acute bipolar mania.
The knowledge base regarding the medical treatment of acute bipolar mania is rapidly expanding. Information about agents with established antimanic properties is increasing, and more agents with putative antimanic properties are being identified. We first review the controlled studies supporting the efficacy of the established antimanic agents lithium, valproate, and carbamazepine and standard ...
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Atypical antipsychotic medications have assumed growing importance for the treatment of bipolar disorder, an illness that affects approximately 1.2%-3.7% of the general population in a given year. Current practice guidelines for the treatment of bipolar mania support the use of atypical antipsychotic medications as monotherapy or as a component of polytherapy, and in clinical settings the use o...
متن کاملcomparison the effectiveness of aripiprazole and risperidone for the treatment of acute bipolar mania
background: second-generation antipsychotics, approved for the treatment of mania, are associated with adverse effects such as weight gain and metabolic disorders. aripiprazole, a recently introduced second-generation antipsychotic, are thought to account for its low propensity for weight gain, metabolic disturbances and sedation. the purpose of this study was to investigate the effect of rispe...
متن کاملQuetiapine for acute mania in bipolar disorder.
PURPOSE The efficacy and tolerability of quetiapine in the treatment of acute mania were reviewed. SUMMARY Five randomized, placebo-controlled trials involving quetiapine as monotherapy or adjunct therapy in combination with either divalproex or lithium in the treatment of bipolar mania in either adolescents or adults were identified and reviewed. The primary outcome measure used in the trial...
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ژورنال
عنوان ژورنال: Frontiers in Pharmacology
سال: 2013
ISSN: 1663-9812
DOI: 10.3389/fphar.2013.00004